Case Report

Case Report
    

Below is an excerpt from one of Dr. Trokoudes's articles which was published in the Journal of Human Reproduction:
  
Human Reproduction vol. 10 no.4 pp.880-882, 1995

Pregnancy with spermatozoa from a globozoospermic man after intracytoplasmic sperm injection treatment

K.M. Trokoudes^1,3,, N. Danos¹, L. Kalogirou¹, R. Vlachou¹, T. Lysiotis¹, N. Georghiades¹, S. Lerios^1, and K. Kyriacou².
   

¹ Pedieos' IVF Center, 8 Karaoli St., Suite 201, Nicosia 162, and 
²The Cyprus Institue of Neurology and Genetics, P.O. Box 3462, Nicosia, Cyprus.
³To whom correspondence should be addressed.

Abstract:  We present a case of third trimester pregnancy occurring in a 29 year old woman after intracytoplasmic sperm injection (ICSI) treatment with spermatozoa from a globozoospermic man.  We believe this is the first reported case.  A 37 year old man was diagnosed with globozoospermia with normal sperm count and motility.  In-vitro fertilization and subzonal insemination treatments failed to achieve fertilization of any eggs.  The ICSI method produced 50% fertilization, 75% cleavage rate and a singleton pregnancy with a female fetus.  No pregnancy or fetal abnormalities have been noted after >7 months of gestation.

This was the first pregnancy delivery achieved worldwide. It was followed by a second successful delivery two years later for the same couple.